This section will contain individual monographs, each of which will review a specific opioid or group of opioids.

 

The monographs will have the following structure: 

• name of the drug with details relating to its discovery and development;

• structure of the drug;

• mechanism of action;

• indications for licensed formulations and regulatory status (MHRA and FDA);

• pharmacokinetic properties;

• pharmacodynamic properties;  

• known contraindications and warnings in licensed use;

• known adverse effects and adverse reactions;

• drug-drug interactions; and

• links to biomedical and clinical trials databases.