This section will contain individual monographs, each of which will review a specific opioid or group of opioids.

 

The monographs will have the following structure: 

  • name of the drug with details relating to its discovery and development;

  • structure of the drug;

  • mechanism of action;

  • indications for licensed formulations and regulatory status (MHRA and FDA);

  • pharmacokinetic properties;

  • pharmacodynamic properties;  

  • known contraindications and warnings in licensed use;

  • known adverse effects and adverse reactions;

  • drug-drug interactions; and

  • links to biomedical and clinical trials databases.